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For nanozymes with multi-enzyme catalytic activities in particular, their stable catalytic function hinges on the dual stabilization of structure and activity provided by the hydrogel carrier

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If we remove the methionine input in the model, the GSH concentration declines to a new steady-state 47% of normal

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In turn, transforming growth factor- (TGF-) expression by astrocytes inhibits NFB signaling, helping to modulate and reduce the neuroinflammatory response ( Molecular and morphological changes during astrogliosis assessed by glial fibrillary acidic protein (GFAP) expression are directly related to the severity of astroglial reactivity, being GFAP overexpression a characteristic sign of neuroinflammation in neurodegenerative processes in the CNS (Sofroniew, 2009)