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Epigenetic modifications have been reported to induce a series of changes in gene expression and protein levels that result in mitochondrial abnormalities and neuronal apoptosis and lead to PD (Zhang et al., 2021), long non-coding RNAs ( Mitochondrial Quality Control in Parkinsons Disease Quality control mechanisms are essential to maintaining a healthy mitochondrial network and cell homeostasis, especially to dopaminergic neurons

But the behavioral tools, such as NSDR, that are well established to improve baseline levels of dopamine have exceedingly high safety profiles and we know increase dopamine

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