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Crude and adjusted rates were analyzed, and temporal trends were evaluated using logistic regression with orthogonal polynomial contrasts for each year

So, if someone was tested by their pediatrician or their PCP and they had Lyme and they got doxycycline, well, its a high likelihood that they have a co-infection as well, and those require different antibiotics or treatments

Feoktistova M, Geserick P, Kellert B, Dimitrova DP, Langlais C, Hupe M, et al

JAMA Network Open, 7 (9), e2440018e2440018

Plasma analysis Blood was collected from the tail vein of the mice in lithium-heparin collection tubes (Sarstedt, #41.1393.105)