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Across previously described studies assessing the fluorescence lifetimes of healthy eyes, the shortest lifetimes appear to be at the foveal and macular regions, with the longest lifetimes appearing at the optic disc

The possible explanation for the increased spontaneous acrosome reaction as seen in this study could be due to inhibition of PKA, actin polymerisation or CAMKII and PLD pathways, which needs to be further interrogated

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