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Recent studies have underscored the role of the TET family of enzymes, a new class of epigenetic regulators that catalyze the conversion of 5-methylcytosine (5-mC) to 5-hydroxymethylcytosine (5-hmC), thereby facilitating DNA demethylation and impacting gene expression (Babar et al

doi: 10.1126/science.aae0491 235 BlundellSRayKKBucklandMWhitePD

In granulosa and adipose cells, VDR activation reduces oxidative-inflammatory cascades, indirectly improving insulin signaling and follicular microenvironment stability (213)