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10.1038/nri3430 32 KangE

Our commitment to quality supports reproducible research outcomes across diverse experimental applications

Low GH and normal/high IGF-I Obesity is a common yet serious condition associated with blunted spontaneous and stimulated GH secretion (87, 88), i.e., a state of relative GHD

This system provides sequential therapeutic action: the DNA component acts as an early scavenger of damaging ROS, while the subsequently active aptamer competitively binds C5a, thereby inhibiting complement activation and downstream inflammatory amplification during later stages of IRI [68]