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Using this compound as a marker of cobalamin deficiency, we have been able to demonstrate that cats and dogs with very low serum cobalamin do indeed have a significant tissue-level cobalamin deficiency (Figure 2)

Wang, L

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Weight loss results are typically noticeable after several weeks of regular injections, particularly when combined with lifestyle adjustments such as improved diet and physical activity

Figure 5: Changes in tissue weight in lean mice and obese mice across the three different experimental treatment groups