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Taken together, these findings indicate that although PRLM levels are elevated in SS-like mouse models, likely as a transient compensatory response to excessive inflammation, this endogenous increase is insufficient to resolve the inflammatory process

Medical supervision helps ensure that: Sleep symptoms are evaluated properly Underlying causes are not missed Safety risks are reviewed Medications and supplements are considered Product sourcing is discussed carefully Expectations are realistic Side effects are monitored Treatment fits the patients overall care plan If someone has untreated sleep apnea, severe depression, panic symptoms, medication-related insomnia, or trauma-related sleep disturbance, DSIP alone would not address the root cause

Some studies used semi-immersive VR, relying on screen-based simulations (Park, 2024

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Food Res Int (2018) 113:1838