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Fe 3 O 4 NPs possess superior biocompatibility and potent Fenton catalytic properties, promoting the robust production of ROS

Diabetic rats and high fat diet (HFD)-fed mice subjected to 4 weeks of treatment with myriocin, an SPT inhibitor, had lower body weight, fasting blood glucose, plasma insulin, and circulating free fatty acid levels compared to diabetic and obese controls (40)

Cellular Repair : It plays a role in DNA synthesis and repair, cell proliferation, and the overall maintenance of cellular health

The activity of GPX4 is regulated by multiple layers, such as epigenetic regulation, transcription regulation and post-translational regulation, among which these regulatory processes involve phosphorylation, ubiquitination, succination and glycosylation (Cui et al., 2022)

Glutathione is active in Phase II liver detoxification, helping the body manage carcinogens, toxins, and drugs