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Another placebo-controlled trial in older adults at high risk of dementia found that supplementation with vitamin C (200 mg/day) and vitamin E (500 mg/day) for 12 weeks did not alter any of the measured cognitive functions despite nonsignificantly lowering levels of F 2 -isoprostanes biomarkers of lipid peroxidation in vivo (176)

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Hormonal therapies are the first choice, before surgery and after surgery, in order to reduce the risk of recurrence