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We therefore examined if neurodegeneration in the GCLC-KO mouse is associated with neuroinflammation

doi: 10.3389/fendo.2021.626390 26 KimSKangSWJooJHanSHShinHNamBYet al

Impairment of the GH-IGF-1 axis may also result from mutations to wider members of the IGF family including the IGFALS gene, as well as STAT5 defects that affect post-GHR signaling [43,44]