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Anemia develops from B12 deficiency, as the vitamin is engaged in the production of healthy red blood cells

mtDNA mutation sequencing Mice tissues (tail, blood, tumor, lung, liver) and cells were lysed with a lysis buffer containing 25mM NaOH and 0.2mM EDTA

This adaptation can also contribute to resistance against therapies that induce oxidative stress or ferroptosis, supporting tumor growth and complicating treatment outcomes

1 Introduction Chronic Kidney Disease (CKD) constitutes a multifaceted clinical entity characterized by the inexorable deterioration of renal architecture and physiological function, representing one of the most formidable challenges in contemporary nephrology (DArrigo et al., 2025

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