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Protocatechuic acid Protocatechuic acid has been shown to reduce PCOS in mice in vivo, and studies conducted in vitro have shown that it has a protective effect by promoting the activation of the PI3K/AKT/mTOR signaling pathway, which suppresses ROS, autophagy, and apoptosis in ovarian granulosa cells [153]

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However, because steroid therapy is associated with a number of adverse effects, such as, but not limited to, high blood pressure, high blood sugar, gastrointestinal issues, and dizziness, patients with these conditions cannot be treated with steroids, and these conditions, as well as ARHL, are widespread in older adults

Discoidin domain receptor 1 (DDR1) is highly expressed in HCC, which promotes glutamine metabolism as fuel by increasing GLUD1, GLS1, and SLC1A (glutamate transporter) in HCC (Lin et al., 2020)

For the standardization of relative GSHGSSG quantification assay, young gravid adult animals were transferred to a snap-cap tube containing S-basal medium and 5% saturated E