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"'Connecticut' could use more of Arnold's muscle"

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Supportive secondary endpoint analyses were not controlled for multiple comparisons and should not be used to infer definitive treatment effects

The resulting accumulation of superoxide radicals further exacerbates oxidative stress, forming a vicious cycle that accelerates the progression of DR

Furthermore, the apoptosis of SGNs detected by C-CASP3 immunostaining and western blot showed that there was much less C-CASP3-positive SGNs and remarkable reduction of the C-CASP3 protein levels in the NAC co-treated groups compared with the peroxynitrite-only groups, and it was also lower in the peroxynitrite + gpx1 / + NAC group compared with the peroxynitrite + gpx1 / group (Figures 7B,C)