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Rigorous clinical investigations are warranted to delineate the regulatory networks influenced by probiotics in colorectal cancer, elucidate their sequential mechanisms of action, and facilitate their integration as adjuvant therapeutic modalities for colorectal cancer prevention and management (302)

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Although these findings suggest the involvement of antioxidant and cytoprotective mechanisms, the evidence remains largely correlative, as the specific molecular targets and signaling pathways directly regulated by scopoletin have not been clearly defined

Nicole Loeffler, freshman, Deans List, College of Education and Human Sciences, elementary education