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The principal function of histone acetylation and methylation is to recruit or repel reader proteins that recognize the small moieties on modified histone residues and transduce the epigenetic signals at chromatin to distinct biological outcomes 4

Meat Sci 116:186192

However, the clinical use of direct TNF- inhibitors for MASH has not yet been approved

Up to 30% of people with NAFLD develop NASH, a serious illness with inflammation and scarring

In the present study, we classified patients of Group-A into two sub-groups, i.e., patients who have persistent fatigue on both HD and HD-free days (Group-A1), and having fatigue on only HD days (Group-A2), based on our hypothesis that they are clinically different entities