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doi: 10.3390/nano13152185 262 SutyakK

Rapid neurotoxicity enhanced by neuronal excitotoxin has been observed with abnormal glutamate levels 60

doi: 10.1016/J.ADDR.2005.07.002

Excessive production of reactive species leads to various pathological diseases such as ulcerogenic, depression, cardiovascular disorders, and rheumatoid arthritis

Glutaminolysis Pathway: As discussed, glutamine is converted to glutamate by glutaminase (GLS), which is then deaminated by glutamate dehydrogenase (GDH) to form -KG