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Alterations in mitochondrial membrane potential in peripheral blood mononuclear cells in Parkinsons disease: potential for a novel biomarker

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References View all 8 references + Sikiri, P., et al

Accordingly, our work indicates that addition of N-glycan on Ea-domain prevents the degradation of proIGF-1Ea by the proteasome, probably overcoming the folding limitation of unglycosylated proIGF-1Ea and its entry into the ER-associated degradation (ERAD) pathway 40,41

Full-length hGH binds to the growth hormone receptor and stimulates IGF-1 production, driving anabolic and proliferative effects across multiple tissue types