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Furthermore, some supplements marketed for "thyroid support" contained actual thyroid hormones , which can pose a risk if the hormone amounts are less or more than needed

Statements Author contributions RE and JB designed the study

Suppressive thyroid hormone therapy aims to shrink benign nodules by keeping TSH levels below 0.5 mU/L, though success varies and requires careful monitoring for hyperthyroidism

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doi:10.1371/journal.pone.0040365 Philippova M, Joshi MB, Pfaff D, Kyriakakis E, Maslova K, Erne P, Resink TJ (2012) T-cadherin attenuates insulin-dependent signalling, eNOS activation, and angiogenesis in vascular endothelial cells