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& Xie, A

10.1007/s10863-008-9155-9 J

Pituitary / Journal of Endocrinological Investigation

A recent study showed that p53 can induce ferroptosis independent of the GSH/glutathione peroxidase 4 (GPX4) axis by downregulating vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1), which prevents the conversion of vitamin K to its antioxidant form, vitamin K hydroquinone (VKH2) (Yang et al