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STAT3 has been found to be activated to promote the occurrence of HCC ( STAT3 mRNA, which led to the increased expression levels of COX-2 and COX-2 mRNA, the increased VEGF level, the reduced cleaved caspase-3 level, the increased viability and migration of HCC cells and the reduction of HCC cells apoptosis

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Antioxidant effects after coffee enema or oral coffee consumption in healthy Thai male volunteers S Teekachunhatean N Tosri C Sangdee R Wongpoomchai W Ruangyuttikarn C Puaninta S Srichairatanakool We designed an open-label, randomized two-phase crossover study to investigate the antioxidant effects after single and multiple doses of a coffee enema versus coffee consumed orally

- Let the syringe reach room temperature