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In diet-induced obese (DIO) mouse models, 5-Amino-1MQ treatment produced significant reductions in body weight, white adipose tissue mass, and adipocyte cell size without significant effects on food intake suggesting a metabolic rather than appetite-suppressing mechanism

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In vitro , NNMTi significantly decreased the intracellular production of MNAM, increased the intracellular levels of NAD + , and inhibited adipogenesis

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GHK-Cu can directly scavenge harmful reactive oxygen species (ROS), thereby mitigating oxidative stress