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10.4161/psb.24536 197 WangZ.XiaoY.ChenW.TangK.ZhangL

Elevated plasma MDA levels may denote increased oxidative damage in the lungs, suggesting its utility as a biomarker for assessing COPD severity and progression

Furthermore, studies suggest that these alkaloids may also directly induce programmed cell death in neurons and glial cells via activation of the PPAR/NF-B/caspase-3-dependent apoptotic pathway, offering a novel explanation for their potential long-term or subacute neurotoxic effects [42]

Martins AS, Jansen AK, Rodrigues LOC, Matos CM, Souza MLR, Miranda DM, et al

Since then, a number of preclinical studies have examined its possible impacts on inflammation, gastrointestinal health, and tissue repair