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Of more than 100 compounds synthesized and tested for TGR inhibition (a more thorough description of compound design will form the basis of a future manuscript), the most promising were selected to be extensively characterized in the in vitro and in vivo studies described below

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Furthermore, the TME critically influences GBM pathogenesis via crosstalk among immune cells, stromal cells, and ECM components [33]

Lung cancer: what are the links with oxidative stress, physical activity and nutrition