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Interestingly, DEX-induced cell death could be rescued by ferroptosis inhibitor Ferrostain-1 (Fer-1), but not by Z-VAD-FMK(the apoptosis inhibitor), NEC-1(the necrosis inhibitors), and VX-765 (the pyroptosis inhibitor) (Fig

O"Byrne, Kathy Gately, Abstract A64: NF"B-I"B" Interaction: A Mechanism of Resistance to Cisplatin in Non Small Cell Lung Cancer (NSCLC), Clinical Cancer Research , 18, (10_Supplement), 2012, pA64 - A64, pA64-A64Journal Article, 2012, DOI Susan Heavey, Martin P

Upon crossing the inner mitochondrial membrane, ALCAR undergoes a fascinating biochemical split

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After treatment, the medium was removed, and 20 L/well of fresh medium containing luminogenic CYP substrate was added, followed by a 1-hour incubation at 37 C