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However, from a genetic perspective, evidence shows that for every 1 standard deviation increase in 25(OH)D level, the relative risk of COPD is reduced by 57.2% (161), and it has a 22% mediating effect on diet-induced inflammation and all-cause mortality in COPD patients, showing a nonlinear L-shaped correlation (162)

conceived the framework, provided guidance and assistance, and made edits to the draft

This improves insulin sensitivity and regulates key metabolic pathways, essentially mimicking the positive metabolic effects of exercise

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