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Tetrahydrocurcumin, a major metabolite of curcumin, ameliorates allergic airway inflammation by attenuating Th2 response and suppressing the IL-4R-Jak1-STAT6 and Jagged1/Jagged2 -Notch1/Notch2 pathways in asthmatic mice

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SIRT1 attenuates endoplasmic reticulum stress and apoptosis in rat models of COPD

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However, the small sample size and preliminary nature of these results warrant confirmation in future studies with larger, more balanced cohorts