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Sulfasalazine induced ferroptosis in breast cancer cells is reduced by the inhibitory effect of estrogen receptor on the transferrin receptor

NETosis is a form of regulated cell death (RCD) characterized by the release of net-like DNA-protein structures (NETs) in response to infection

They reported that the medication delivered therapeutic benefits with minimal side effects

401,402,403 Furthermore, CKD patients demonstrate systemic inflammation and elevated levels of pro-inflammatory cytokines like C-reactive protein (CRP), TNF-, IL-6 and IL-1

Treatment with the ferroptosis inhibitors deferoxamine (DFO) and liproxstatin-1 can rescue the sensitivity of CagA-induced cells to RSL3 and erastin, suggesting a potential therapeutic strategy for inducing ferroptosis in GC patients infected with CagA+ H