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Treatment and assessment of therapeutic response in the study patients Group 1 patients were treated with the combination of hydroxycarbamide (500 mg capsules)

The Journal of Steroid Biochemistry and Molecular Biology, 200, 105607

Glucomannan also delays stomach emptying, slowing the digestion and absorption of all nutrients, including carbohydrates, which leads to lower blood glucose levels and prevents major spikes in insulin

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As shown in Figure 3C, the keto group of ring A interacts with the side chains of amino acids Q711 and R752, whereas the hydroxyl group at the 17-position hydrogen-bonds with the side chains of N705 and T877