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This article summarizes what preclinical studies have explored, including proposed mechanisms such as vascular signaling and inflammatory modulation

The presence of oxidative stress markers and ferroptosis-related damage in placental tissues further supports the involvement of ferroptosis in RM pathophysiology (Xie et al., 2024)

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2 Materials and method A comprehensive literature search was conducted using databases such as PubMed Central, Medline, SpringerLink, Research Gate, and Google Scholar

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