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miR-552-3p modulates transcriptional activities of FXR and LXR to ameliorate hepatic glycolipid metabolism disorder

In a controlled, open trial with psoriasis patients, secukinumab did not cause liver enzyme elevations, while methotrexate led to a threefold increase in liver enzymes in 4 of 64 patients, necessitating withdrawal (Gisondi et al

PaCran delivers proanthocyanidins that help prevent bacterial adhesion to urinary tract walls, offering protection against UTIs through an anti-adhesive mechanism rather than antimicrobial action

Ratziu V, Giral P, Jacqueminet S, Charlotte F, Hartemann-Heurtier A, Serfaty L, Podevin P, Lacorte JM, Bernhardt C, Bruckert E, Grimaldi A, Poynard T, LIDO Study Group

2025