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Description

A flexible region (residues 74 to 88) forms a wall to the active site cavity (termed flexible wall), while it becomes ordered upon binding of the reaction intermediate bound, thus serving as a gate to the active-site cavity

doi: 10.1021/acsami.9b06162

Most available data consists of observational reports from weight loss clinics where multiple interventions (caloric restriction, exercise programs, behavioral counseling) are implemented simultaneously, making it impossible to isolate the contribution of lipotropic injections