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However, there is still a significant difference between the WL that can be achieved with bariatric surgery and the currently approved obesity pharmacotherapies and there is heterogeneity in treatment responses with GLP-1 RA (for example people with T2D may achieve less WL compared to those without diabetes in clinical trials, despite similar lifestyle interventions) [13, 14]

Reported MOTS-c side effects are generally mild and transient, most commonly consisting of localized injection site reactions such as redness, itching, or minor discomfort

While inhaled corticosteroids like budesonide can have minimal systemic absorption, the risk of decreased bone mineral density is primarily associated with long-term, high-dose use rather than short-term or intermittent rescue use of Airsupra

Is 250 mcg the same as 0.25 mg

Even modern biologics have a low-to-moderate response rate