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We summarize the completed clinical trials and those terminated due to low efficacy or severe side effects for these therapies in CNS diseases, as shown in Table 2

A growing body of clinical evidence indicates that tumors harboring BRCA1/2 mutations derive the greatest benefit

In some cases, these effects may resolve on their own once treatment is stopped and the drug is eliminated from the body [115]

RNA-seq of TGF-treated hHSCs and spatial transcriptomics of CCl4-murine models showed increased ADAMTSL2 expression (log FC 5.8, p=2.37E-91, n=3)

Maternal dietary zinc supplementation prevents aberrant behavior in an object recognition task in mice offspring exposed to LPS in early pregnancy