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Timofeeva AM, et al

Thus, conditioned-media approaches can support metabolite screening but cannot replace direct Gut-on-a-Chip co-culture for modeling microbiome-dependent first-pass metabolism

Imagine multiple taps pouring water into a bucket

Furthermore, polydopamine (PDA) nanoparticles loaded with Ce6 molecules can be synergized with phototherapy to release antigens thereby triggering DCs maturation and helping to inhibit tumor metastasis and recurrent (109)

170 Several inhibitors are under development, one of which has entered clinical trials, but no effective anti-inflammatory effect has been demonstrated