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Lipopolysaccharide (LPS), a characteristic component of the outer membrane of Gram-negative bacteria, was used to induce a mouse model of acute lung injury

Multiple experimental studies have demonstrated that curcumin attenuates ischemic and toxic renal injury by suppressing TLR4/NF-B activation, reducing oxidative stress, and downregulating pro-inflammatory cytokines, including IL-1, IL-6, and TNF- (Youn et al