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3.8 Xenobiotics and neurotoxicity 3.8.1 Background Xenobiotics are chemical substances foreign to the human body, commonly found in pharmaceuticals, food additives, pesticides and environmental pollutantsmaking exposure unavoidable (Jin et al., 2023)

It is not intended for human consumption, therapeutic use, or medical application

These results tentatively suggest that GHK-Cu might help mitigate the inflammatory responses triggered by cigarette smoke

When evaluating the stability in the presence of HSA at 35 mg/mL (reflecting the average plasma concentration of HAS), results showed that the FA-CMC-GNA NPs size remained stable over the 72-h period, with an average diameter maintained at 305.4 nm and no observable aggregation

For individuals with Wilson's disease (a genetic disorder causing copper accumulation) or other copper metabolism disorders, theoretical caution is warranted, though even in these populations topical GHK-Cu is unlikely to pose significant risk given the minimal systemic absorption