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Navitoclax (ABT263) reduces inflammation and promotes chondrogenic phenotype by clearing senescent osteoarthritic chondrocytes in osteoarthritis

Brigitte Knig

Rather than focusing solely on therapeutic efficacy, this work integrates material design, localized drug delivery, and biological evaluation to explore a rectally administered strategy aimed at enhancing local radioprotection while minimizing systemic exposure

oxidatively modified Prx2 has been found in Alzheimers disease patients [85]

Three lipoxygenases, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase (5-LOX, etc.), are the major LOX isoforms found in humans (Table 43-4)