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In comparison with FXa that does not contain the modifications, the relative dependence of the cofactor is increased at least 2 times, 3 times, 4 times, 5 times, 6 times, 7 times, 8 times, 9 times, 10 times, 20 times, 30 times, 40 times, 50 times, 60 times, 70 times, 80 times, 90 times, 100 times, 200 times, 300 times, 400 times, 500 times, 600 times, 700 times, 800 times, 900 times, 1000 times, 1500 times, 2000 times, 2500 times, 3000 times, 4000 times, 4,500 times, 5,000 times, 6000fold, 7,000 times, 8,000 times, 9,000 times, 10,000 times, 15,000 times, 20,000 times or more

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10.3892/etm.2012.710 Exp