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5.1.2 Coordination between hepatic detoxification and renal excretion The liver, serving as the central node of the gut-liver-kidney axis, plays a critical role in DKD progression through its metabolic dysfunction

Effects of combined low-dose spironolactone plus vitamin E vs vitamin E monotherapy on insulin resistance, non-invasive indices of steatosis and fibrosis, and adipokine levels in non-alcoholic fatty liver disease: A randomized controlled trial

Glutathione is a naturally occurring antioxidant that is present in every cell of the body

H., Kim, S., Choe, M

In the presence of reduced concentrations of BH 4 , eNOS becomes uncoupled and transfers electrons to molecular oxygen instead of L-arginine to produce superoxide rather than NO