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Viral proteins as well as host damage-associated molecular patterns, that accumulate following cellular stress during viral infection, were linked to TLR4 activation, with uncontrolled TLR4 activation being associated with severe disease (Olejnik et al., 2018)

Figure 6: Effect of 6-weeks oral treatment with H.pylori eradication therapy(1), nizatidine alone and in combination with either vitamin E or thioctic acid or a combination of both on blood SOD activity in H.pylori -infected duodenal ulcer patients as compared with pre-treatment and normal control values