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doi: 10.1038/ncomms6439 9 ArnonD

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Folate monoglutamates, including synthetic folic acid, are absorbed in the duodenum and upper part of the jejunum by the highaffinity protoncoupled folate transporter PCFT1, encoded by SLC46A1, where folic acid requires a further reduction reaction by dihydrofolate reductase (DHFR) and the riboflavin dependent enzyme, methylene tetrahydrofolate reductase (MTHFR), to form 5-methyl-tetrahydrofolate (5-MTHF)

Tesamorelin: Structure and Mechanism Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH)

Several placebo-controlled and/or random trials have investigated the effect of amifostine on the neurotoxicity induced by cisplatin, carboplatin, doxorubicin and paclitaxel