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Pharmacologic inhibition of AKT by treatment with the AKT inhibitor MK2206 significantly decreased GSH levels in untreated TrC1 AKT-E17K cells and almost abrogated GSH levels 12 h after irradiation, and this was associated with a significantly increase in radiosensitivity

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332 : 213221 Kokame K, Agarwala KL, Kato H and Miyata T (2000) Herp, a new ubiquitin-like membrane protein induced by endoplasmic reticulum stress

Although early research on folic acid focused on treating a specific form of anemia, Kumar (24), was the first to identify key elements of folic acid metabolism associated with acute lymphoblastic leukemia in children

Ishola I, et al