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Firstly, it can be displaced from the binding pocket by endogenous substrates, which consequently hinders its efficacy

The influence of vitamin C and e or beta-carotene on peroxidative processes in persons with myocardial ischemia

conducted a cohort study including 11,169 participants, with a median follow-up period of 24.1 years [115]

doi: 10.1007/s00726-007-0560-x 38 VorobjevaNVChernyakBV

Epigenetic modifications in ARCs Epigenetic modifications represent heritable changes in gene expression that occur independently of alterations in the underlying DNA sequence (40)