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PMID: 27847966

However, B12 levels can rise regardless of whether treatment is effective

Loading phases may run 4 to 6 weeks at the higher end of the range, followed by a maintenance dose of 1 mg/day 3 to 5 times per week

Thymosin beta-4 has neuroprotective data as well, particularly in traumatic brain injury models

The one constant is consistency of timing and route for a mechanism that works by gradually shifting cellular metabolism, day-to-day steadiness matters more than any single dose