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Discovery of 4-[(5-arylidene-4-oxothiazolidin-3-yl)methyl]benzoic acid derivatives active as novel potent allosteric inhibitors of protein tyrosine phosphatase 1B in silico studies and in vitro evaluation as insulinomimetic and anti-inflammatory agents Eur

Intestinal permeability and colorectal cancer Increase in intestinal permeability may predispose susceptible individuals to the development of colorectal cancer (CRC)

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PMID: 28042564 Lappinga PJ, Abraham SC, Murray JA, Vetter EA, Patel R, Wu TT