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10.1016/j.nano.2017.01.014 111 WangZ.LiuY.XiaoY.XieY.WangR.ZhangY.et al (2022)

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[19] Augmentation [edit] If therapy with antidepressants (such as selective serotonin reuptake inhibitors [SSRIs]) does not fully treat and discontinue [38] the symptoms of major depressive disorder (MDD) (also known as refractory depression or treatment resistant depression [TRD]) [39] then a second augmentation agent is sometimes added to the therapy

Doctors usually begin with a low dose of semaglutide, such as 0.25 mg, given once a week as a subcutaneous injection

10.1016/j.bbrc.2016.10.086 Biochem Biophys Res Commun