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Zhang CL, Zhang S, He WX, Lu JL, Xu YJ, Yang JY

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mGluR5 expression in reactive astrocytes is persistently upregulated following electrically induced SE in a kindling model and in TLE ( Multiple studies have shown that mGluR5 levels are also increased in patients with TLE ( It is important to note that activation of mGluR5 has also been shown to lead to increased excitability