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J Bacteriol 192:41724180 Mancini S, Abicht HK, Gonskikh Y et al (2015) A copper-induced quinone degradation pathway provides protection against combined copper/quinone stress in Lactococcus lactis IL1403

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The scenario suggested by today's literature points towards drug-specific CD8+cytotoxic T cells utilising perforin/granzyme B trigger keratinocyte apoptosis.6 In TEN, several studies stated a predominance of CD8+ T lymphocytes along dermoepidermal junction, in the epidermis, or in the blister fluid of early blisters.711 In keeping with these findings, Behrendt et al.12 reported a higher percentage of perforin positive CD8+ T lymphocytes in PBMC of patients with SJS on the day of their admission than in healthy donors

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