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Studies have also shown that disulfiram-copper (DSF-Cu) can inhibit aldehyde dehydrogenase (ALDH), targeting cancer stem cells, and therefore has a synergistic effect on the chemoresistance of tumor stem cells that affect sorafenib treatment outcomes (199)

The C129S mutant of PGRMC1 also interacted with endogenous PGRMC1 and EGFR (Supplementary Fig

Its calming effect on the central nervous system can help reduce tension and promote a greater sense of calm

Comparisons with previous in vivo studies with praziquantel suggests that these inhibitors outperform the drug of choice for schistosomiasis against juvenile worms

These inorganic PTAs exhibit high photothermal conversion efficiency, good photothermal stability, and good inhibitory effects on cancer cells [93,94,95]